Hibernian and Motherwell to open Quarter-Final weekend on Saturday night.
Motherwell, St Mirren and Dundee United book their place in the Fifth Round following a Friday night of action.
The Scottish Cup continues apace this weekend, as the Fourth Round kicks off with a bumper Friday night feast.
Find out about the rules and regulations of the 2020-21 Scottish Cup.
Delve into the Scottish Cup archives to look back at previous seasons of the Scottish Cup competition.
Find out more about the Scottish Youth Cup including the latest news, results, fixtures and previous winners.